Legg–Calvé–Perthes Diseass

Legg–Calvé–Perthes disease

The Article by Dr Vinod Urade

Legg–Calvé–Perthes disease (LCPD, also known as Perthes disease or Legg–Perthes disease) is a childhood hip disorder initiated by a disruption of blood flow to the head of the femur. Due to lack of blood supply bone becomes die it is Osteonecrosis or Avascular Necrosis ,The loss of bone mass occures and weakness may starts it is Commonly affected Femoral head.

This condition commonly occurers in childrens Of Age 4-8 Years but it may Sometimes upto 2 to 15 Years of Age.

In LCPD,Their is Permanently deformity occures of Hip joint ( the ball and Socket variety of joint is disterbed ;
femoral head can not fix in the Acetabulam cavity of hip )

CAUSES
The Cause Are may sometimes unknown.but it is commonly occures due to Loss of blood supply to the Head of Femur.The lack of blood supply may also occures this condition.Other causes includes Infection,Inflammation.

Sign And Symptoms

Symptoms including Hip and knee pain.it may referred to groin region also. Pain Increased during Joint activity Especially Internal rotation of hip.

DIAGNOSIS

Diagnosis of LCPD
Xray
MRI
Other Radiological Investigations for bone scan.

TREATMENT

Homoeopathy having great scope in Curing LCPD.
Other Treatment including Physiotherapy,Traction having Some results.

Thanks for Visiting us You can Now Subscribe Newsletter for FREE !! Click Subscribe button Over the Header.

Duchenne muscular dystrophy

Duchenne muscular dystrophy by Dr Vinod Urade

*Duchenne muscular dystrophy* (DMD) is a genetic disorder characterized by progressive muscle degeneration and weakness. Causes muscular dystrophy.

DMD is caused by an absence of  *dystrophin*  protein that helps keep muscle cells intact. Symptom onset is in early childhood usually between ages 3 and 5 Commonly boys. The disease primarily affects boys, but in rare cases it can affect girls.

*Symptoms of DMD*

_Muscle weakness_ can begin as early as age 3, first affecting the muscles of the hips, pelvic muscles, thighs and shoulders, and later the skeletal (voluntary) muscles in the arms, legs and trunk. The calves often are enlarged. By the early teens, the heart and respiratory muscles also are affected. For more about DMD symptoms, see Signs and Symptoms.

Becker muscular dystrophy (BMD) is a milder version of DMD. Its onset is usually in the teens or early adulthood, and the course is slower and less predictable than that of DMD.

*Causes*

first described by the French neurologist *Guillaume Benjamin Amand Duchenne* in the 1860s, but until the 1980s, little was known about the cause of any kind of muscular dystrophy. In 1986. the protein associated with this gene was identified and named dystrophin. Lack of the dystrophin protein in muscle cell.
Mutation on gene "locus xp21"

DMD has an X-linked recessive inheritance pattern and is passed on by the mother, who is referred to as acarrier. For more about the way gene mutations cause Duchenne dystrophy, see Causes/Inheritance.

_____________________________________
(Source:Internet)